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The dihydropyridine derivative is a blocker of “slow” calcium channels (SCCC), has a hypotensive and antianginal effect. Blocks “slow” calcium channels, reduces the transmembrane transition of calcium ions into the cell (more into vascular smooth muscle cells than into cardiomyocytes). The antianginal effect is due to the expansion of coronary and peripheral arteries and arterioles:

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Nicergoline is a traditional ergoline preparation that improves metabolism and blood supply to the brain, reduces platelet aggregation, improves hemorheological blood parameters, and accelerates blood flow in the upper and lower extremities. Long-term treatment with nicergoline results in sustained improvements in cognitive function and a reduction in behavioral changes associated with dementia. Acute and chronic changes in cerebral metabolism and blood supply (cerebrovascular stiffness, arterial hypertension, thrombosis and occlusion of cerebral vessels, especially transient cerebral attacks, vascular dementia (dose 30 mg), headache due to vasoconstriction), are used for acute and chronic changes in peripheral vessels. metabolism and blood supply (organic and functional disorders of the arteries of the hands and feet, Raynaud's disease, syndrome caused by loss of peripheral blood flow).

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